For a long time I had this simplistic view that senescent cells accumulate with age, contributing to many age-related degenerative diseases through the sterile inflammation and regeneration impairment they cause. I also thought their removal with the help of drugs is the only possible solution to get rid of them. Destroying senescent cells shouldn’t be…… Continue reading Immunotherapy for senescent cell removal – lessons from human embryo development and other species
Tag: apoptosens
How to avoid the adverse reactions of senolytics through better design
There is no coincidence that cancer is more frequent as we age. And it is also no coincidence that many anti-aging therapies destined for rejuvenation could allow unleashed growth to take place and cause cancer. Hence my interest in those species which despite an abundant capability to regenerate their damaged tissues, show no increased rate…… Continue reading How to avoid the adverse reactions of senolytics through better design
How to engineer negligible senescence in humans – part VII OncoSENS
What is the number one disease killing our elders besides heart disease? Cancer. A dreadful word that conjures all sorts of evil things, cancer runs rampant as we age. What do all cancers have in common? They start from one (or several) nuclear mutation(s). In the case of lifestyle non-inherited cancers the disease…… Continue reading How to engineer negligible senescence in humans – part VII OncoSENS
How to engineer negligible senescence in humans – part VI RepleniSENS
After a couple of previous articles we reached part VI – the most important of all (in my opinion) because a cell that divides itself in two also dilutes its original damage as well. Having a fresh supply of somatic cells derived from our own DNA would largely correct many of geriatrics diseases. Let’s find…… Continue reading How to engineer negligible senescence in humans – part VI RepleniSENS