One of the most disturbing symptoms that occur with aging is rigidity. Humans become stiffer with age, not only in mentality but also physically. Flexibility is in short supply with age as fibroblasts get activated for any tiny injury and respond by excessively depositing extracellular matrix components. For this reason alone, fibrosis – especially excessive […]
During my previous post I mentioned how the evolutionary theory of aging was tested empirically by selective breeding of fruit flies for longevity and later on for shorter lifespans. The longer lived fruit flies obtained in the lab got the nickname of Methuselah flies. Displaying a longer mean and maximum lifespan, they expressed hundreds of […]
I was a college student when I first stumbled upon the “Ending Aging” book by Dr. Aubrey de Grey. I read that book cover to cover but I never got highly enthusiastic about SENS since there were important details which didn’t make sense. The types of damage that humans incur as they age are excellently […]
Rome wasn’t built in a day and neither is longevity attained overnight. A few years ago I read about the compound effect: it’s this idea that baby steps done regularly lead to extraordinary results on the long term. Exponential growth is very hard for humans to wrap their minds around. Linear growth is so much […]