How to engineer negligible senescence in humans – part V ApoptoSENS

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Where does aging start? There is something inside us that makes us frailer as we count more years – in the beginning we will feel more tired, afterwards we may see our first wrinkles and our graying hair. What’s going on? Where does this time bomb start?  Which is the first to age: the body…… Continue reading How to engineer negligible senescence in humans – part V ApoptoSENS

How to engineer negligible senescence in humans – part IV GlycoSENS

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Have you ever started from one of these: and obtained these? This is exactly what happens in our bodies as we age, the only difference being that it takes place in decades instead of hours. Chemically it is called the Maillard reaction. What are extracellular crosslinks and how do they form? We burn slowly and…… Continue reading How to engineer negligible senescence in humans – part IV GlycoSENS

How to engineer negligible senescence in humans – part III AmyloSENS

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Whether aging is a real disease or not, many changes – both morphological and physiological – take place as we count more years on our birthday cake. After a previous discussion on the mitochondrial mutations – the powerhouses of our cells – and the degree of intracellular junk that accumulates each year, time has come…… Continue reading How to engineer negligible senescence in humans – part III AmyloSENS

How to engineer negligible senescence in humans – part II LysoSENS

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Have you ever seen these kinds of people? mid-life obese smokers addicted to junk food, grills and lacking the daily salad Did you notice they look too old for their chronological age? Why is that? As a species which does age, we develop housekeeping issues as we age: our cells accumulate many types of intracellular…… Continue reading How to engineer negligible senescence in humans – part II LysoSENS