Immunotherapy for senescent cell removal – lessons from human embryo development and other species

For a long time I had this simplistic view that senescent cells accumulate with age, contributing to many age-related degenerative diseases through the sterile inflammation and regeneration impairment they cause. I also thought their removal with the help of drugs is the only  possible solution to get rid of them. Destroying senescent cells shouldn’t be…… Continue reading Immunotherapy for senescent cell removal – lessons from human embryo development and other species

Longevity and the Compound Effect

Rome wasn’t built in a day and neither is longevity attained overnight. A few years ago I read about the compound effect: it’s this idea that baby steps done regularly lead to extraordinary results on the long term. Exponential growth is very hard for humans to wrap their minds around. Linear growth is so much…… Continue reading Longevity and the Compound Effect

Long-lived bivalves – what makes them tick for so long?

While extreme longevity and negligible senescence are generally the domain of plants and colonial animals, bivalves as a group rock the boat when it comes to long-lived non-colonial animals. But whether it’s because they live for so long – and research budgets are so low – or whether it’s because it’s too easy to default…… Continue reading Long-lived bivalves – what makes them tick for so long?

Career choice, early retirement and longevity

I could have picked any specialty years ago after I passed the residency exam, but I chose geriatrics to the shock of everyone. I wanted to have the specialty with the wisest patients and even if I’m not practicing it anymore for reasons I’ll detail below, I don’t regret anything. It was impossible for elderly…… Continue reading Career choice, early retirement and longevity